Synthesis of thiadiazine-3,7-diamine derivatives

نویسندگان

  • Nima Razzaghi – asl Department of pharmaceutical chemistry , ardabil university of medical sciences , ardabil , iran
چکیده مقاله:

New 1,5-tetra alkyl methyl- phenyl-1H-pyrimido[4,5-e][1,3,4]thiadiazine-3,7-diamine were synthesized via the cyclocondensation of 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine with phenylthioisothiocyanate and further replacement of chlorine atom on the seven number position of pyrimido[4, 5- e][1, 3, 4]thiadiazin by appropriate secondary amines in simple and efficient methods.

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عنوان ژورنال

دوره 4  شماره 1

صفحات  45- 54

تاریخ انتشار 2014-06-01

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